Endocannabinoid-mediated potentiation of nonnociceptive synapses contributes to behavioral sensitization
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چکیده
منابع مشابه
Nonnociceptive afferent activity depresses nocifensive behavior and nociceptive synapses via an endocannabinoid-dependent mechanism.
Previously, low-frequency stimulation (LFS) of a nonnociceptive touch-sensitive neuron has been found to elicit endocannabinoid-dependent long-term depression (eCB-LTD) in nociceptive synapses in the leech central nervous system (CNS) that requires activation of a presynaptic transient receptor potential vanilloid (TRPV)-like receptor by postsynaptically synthesized 2-arachidonoyl glycerol (2-A...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2018
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00092.2017